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Table 1 Baseline characteristics of the subjects

From: Whole blood RNA sequencing reveals a unique transcriptomic profile in patients with ARDS following hematopoietic stem cell transplantation

Characteristics

ARDS

ARDS-HSCT

Sepsis

Sepsis-HSCT

P (all groups)

P (ARDS vs ARDS-HSCT)

N

6

5

7

5

  

Age

46 (37–60)

39 (25–52)

50 (26–59)

55 (61–42)

0.27

0.41

WBC

6.9 (3.1–16.8)

11 (2.8–19.1)

9 (4–42.1)

8.6 (6.5–29.9)

0.88

0.86

% Neutrophils

87 (71–98)

95 (88–98)

86 (63–95)

80 (65–96)

0.14

0.10

% Lymphocytes

6 (1–18)

2 (0–10)

10 (1–21)

10 (1–21)

0.26

0.12

% Monocytes

4 (1–15)

2 (0–4)

4 (1–11)

9 (0–11)

0.39

0.46

Sepsis

33.3%

40.0%

100%

100%

 

1

Vasopressors

50%

60%

29%

40%

0.8

1

Days since HSCT

 

117 (50–490)

 

148 (50–1322)

  

APACHE II

27.5 (21–47)

30.0 (24–38)

18 (14–40)

19 (14–32)

0.10

0.58

ICU Mortality

67%

100%

14%

0%

0.001

0.45

Mechanical Ventilation

100%

100%

29%

40%

0.04

1

P/F ratio

70.0 (41–205.0)

81.3 (66.0–109.2)

   

0.83

Tidal volume (mL/kg)

5.6 (5.2–7.6)

6.5 (4.5–16.5)

   

0.46

Corticosteroids

50%

100.0%

57%

100%

0.04

0.18

Etanercept

0.0%

80.0%

0%

0%

 

0.02

Other Immunosuppression

50.0%

80%

0%

60%

0.02

0.5

ARDS etiology

      

 Pneumonia, influenza

33%

0%

    

 Pancreatitis

17%

0%

    

 Idiopathic pneumonia syndrome

0%

100%

    

 Idiopathic/CVD

50%

0%

    

Infection

      

 Type

      

  Bacterial

0%

0%

100%

80%

  

  Viral

33%

0%

0%

20%

  

Source

      

 Blood

0%

0%

43%

60%

  

 Lung

33%

0%

14%

20%

  

 GI

0%

0%

57%

0%

  
  1. Idiopathic/collagen-vascular disease (CVD) diagnoses include acute interstitial pneumonia, cryptogenic organizing pneumonia, and collagen-vascular disease associated interstitial lung disease. Values given as median (range)