Skip to main content

Table 1 Baseline characteristics of the subjects

From: Whole blood RNA sequencing reveals a unique transcriptomic profile in patients with ARDS following hematopoietic stem cell transplantation

Characteristics ARDS ARDS-HSCT Sepsis Sepsis-HSCT P (all groups) P (ARDS vs ARDS-HSCT)
N 6 5 7 5   
Age 46 (37–60) 39 (25–52) 50 (26–59) 55 (61–42) 0.27 0.41
WBC 6.9 (3.1–16.8) 11 (2.8–19.1) 9 (4–42.1) 8.6 (6.5–29.9) 0.88 0.86
% Neutrophils 87 (71–98) 95 (88–98) 86 (63–95) 80 (65–96) 0.14 0.10
% Lymphocytes 6 (1–18) 2 (0–10) 10 (1–21) 10 (1–21) 0.26 0.12
% Monocytes 4 (1–15) 2 (0–4) 4 (1–11) 9 (0–11) 0.39 0.46
Sepsis 33.3% 40.0% 100% 100%   1
Vasopressors 50% 60% 29% 40% 0.8 1
Days since HSCT   117 (50–490)   148 (50–1322)   
APACHE II 27.5 (21–47) 30.0 (24–38) 18 (14–40) 19 (14–32) 0.10 0.58
ICU Mortality 67% 100% 14% 0% 0.001 0.45
Mechanical Ventilation 100% 100% 29% 40% 0.04 1
P/F ratio 70.0 (41–205.0) 81.3 (66.0–109.2)     0.83
Tidal volume (mL/kg) 5.6 (5.2–7.6) 6.5 (4.5–16.5)     0.46
Corticosteroids 50% 100.0% 57% 100% 0.04 0.18
Etanercept 0.0% 80.0% 0% 0%   0.02
Other Immunosuppression 50.0% 80% 0% 60% 0.02 0.5
ARDS etiology       
 Pneumonia, influenza 33% 0%     
 Pancreatitis 17% 0%     
 Idiopathic pneumonia syndrome 0% 100%     
 Idiopathic/CVD 50% 0%     
Infection       
 Type       
  Bacterial 0% 0% 100% 80%   
  Viral 33% 0% 0% 20%   
Source       
 Blood 0% 0% 43% 60%   
 Lung 33% 0% 14% 20%   
 GI 0% 0% 57% 0%   
  1. Idiopathic/collagen-vascular disease (CVD) diagnoses include acute interstitial pneumonia, cryptogenic organizing pneumonia, and collagen-vascular disease associated interstitial lung disease. Values given as median (range)