Outcome | Cochrane Meta-analysis 2015 [9]a | Present work |
Mortality | Favours poractant-α (for some types of mortality)b | Trend favouring poractant-α |
BPD | No difference | Favours poractant-α |
Airleaks | No difference | Favours poractant-α |
Lung haemorrhage | No difference | Favours poractant-α |
BPD/mortality | Favours poractant-α | Favours poractant-α |
Re-treatment | Unknown or favours poractant-αc | Favours poractant-α |
Effect of confounder | Cochrane Meta-analysis 2015 | Present work |
Prenatal steroids | Unknown | Not significant |
Gestational age | Unknown | Influences effect size on BPD and need for retreatment |
Poractant-α dose | Unknown | Unknown |