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Table 5 Reason for end of follow-up in enrolled IPF patients

From: Effect of pirfenidone on lung function decline and survival: 5-yr experience from a real-life IPF cohort from the Czech EMPIRE registry

 

Pirfenidone (N = 383)

No-antifibrotics (n = 218)

P-value (pirfenidone vs no-antifibrotics)

Number of lost patients (%)

141 (36.8%)

161 (73.9%)

< 0.001

Deatha

101 (26.4%)

121 (55.5%)

< 0.001

< 12 months

37 (9.7%)

32 (14.7%)

< 0.001

12–24 months

39 (10.2%)

23 (10.6%)

> 24 months

22 (5.7%)

66 (30.3%)

Lost to follow-up

24 (6.3%)

33 (15.1%)

0.001

< 12 months

11 (2.9%)

16 (7.3%)

0.002

12–24 months

9 (2.3%)

7 (3.2%)

> 24 months

4 (1.0%)

10 (4.6%)

Lung transplantation

7 (1.8%)

0 (0.0%)

0.052

< 12 months

1 (0.3%)

0 (0.0%)

0.345

12–24 months

2 (0.5%)

0 (0.0%)

> 24 months

4 (1.0%)

0 (0.0%)

Other

9 (2.3%)

7 (3.2%)

0.601

< 12 months

4 (1.0%)

3 (1.4%)

0.885

12–24 months

2 (0.5%)

1 (0.5%)

> 24 months

3 (0.8%)

3 (1.4%)

  1. aThe date of death is missing in 3 patients treated by pirfenidone