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Table 5 Dams exhibited signs of obesity when fed a high fat diet for 29 weeks

From: Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams (female mice)

Outcome

LFD

HFD

Body weight (g)

26.1 ± 0.5

38.5 ± 1.8*

Body length (snout to vent) (mm)

88.9 ± 0.8

96.4 ± 0.7*

Body mass index (kg/m2)

3.30 ± 0.08

4.14 ± 0.18*

Gonadal white adipose tissue (g)

0.52 ± 0.10

3.84 ± 0.35*

  1. *p < 0.05, compared with dams fed a LFD (student’s t test)
  2. From 4 weeks of age, C57Bl/6 J female mice (n = 28) were separated into 2 treatment groups and fed either a low fat diet (LFD, n = 14) or high fat diet (HFD, n = 14) for 29 weeks. Female mice were mated with male C57Bl/6 J mice after dams were fed either diet for 12 weeks. Three weeks later, offspring were born. Dams were re-mated 1 week after their first litters were removed at 2 weeks of age. Data are shown as mean ± SEM for n = 13–14 dams/treatment