Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams (female mice)

Table 3 Fewer litters born to dams fed a high fat diet survived until 2 weeks of age

*p < 0.05, compared with dams fed a LFD (using Fisher’s; Exact Test)
From 4 weeks of age, C57Bl/6 J female mice (n = 28) were separated into 2 treatment groups and fed either a low fat diet (LFD, n = 14) or high fat diet (HFD, n = 14). Female mice were first mated with C57Bl/6 J male mice after dams had been fed either diet for 12 weeks. Three weeks later, offspring were born. Dams were re-mated 1 week after their first litters were removed at 2 weeks of age. The numbers of offspring (male or female) per litter are reported for pups that survived until 2 weeks of age. Data are shown as mean ± SEM

ISSN: 1465-993X