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Fig. 1 | Respiratory Research

Fig. 1

From: Phospholipase Cε plays a crucial role in neutrophilic inflammation accompanying acute lung injury through augmentation of CXC chemokine production from alveolar epithelial cells

Fig. 1

Effects of the PLCε genotypes on the development of LPS-induced ALI. a Effects on LPS-induced alteration of the alveolar capillary barrier . The total protein in BALF was measured. BALF was collected in 24 h after i.t. administration of LPS (5 mg/kg) or vehicle. n = 9 in the LPS-treated group, and n = 6 in the vehicle-treated group. * p < 0.05 between control and LPS administration, #, p < 0.05 between PLCε genotypes. b Lung edema was evaluated by determining the wet/dry ratios of the lung tissue isolated from mice in 24 h after i.t. administration of LPS or vehicle (n = 8 in the LPS-treated group and n = 4 in the vehicle-treated group). *, p < 0.05 between control and LPS administration, #, p < 0.05 between PLCε genotypes. c Histologic analysis of the lung. Lung sections were prepared in 24 h after administration of LPS or vehicle as in a, and they were stained with H&E. n = 3 in each group. Scale bar, 100 μm

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Respiratory Research

ISSN: 1465-993X

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