Table 1 The L/BW ratio and serum parameters as adverse effects of RXR agonists

L/BW ratio

0.050 ± 0.002

0.049 ± 0.001

0.053 ± 0.001^#

0.073 ± 0.002^*, #, ##

TG (mg/dl)

173 ± 12

140 ± 11*

177 ± 11^#

255 ± 17^*, #, ##

Glucose (mg/dl)

482 ± 23

479 ± 21

565 ± 35

492 ± 30

AST (IU/L)

125 ± 13

151 ± 12

153 ± 19

123 ± 12

ALT (IU/L)

56 ± 9

66 ± 7

54 ± 5

31 ± 4^*, #, ##

ALP (IU/L)

275 ± 10

303 ± 9

296 ± 6

406 ± 11^*, #, ##

LAP (IU/L)

54 ± 2

51 ± 1

53 ± 1

52 ± 1

AMY (IU/L)

5352 ± 509

4608 ± 276

5155 ± 445

6049 ± 204^#