Table 1 Multivariate linear regression analysis of baseline variables with change in airway hyperresponsiveness to small particle adenosine (ΔPD20) as dependent variable in patients treated with QVAR, Clenil and Flixotide
| Â | Baseline predictors | B | 95% CI | p-value | R2 |
|---|---|---|---|---|---|
ΔPD20 QVAR | Age, years | −0.10 | − 0.06; 0.04 | 0.703 | 0.64 |
Sex, male/ female | 0.41 | −0.78; 1.60 | 0.485 | ||
Current smoking, yes/no | −0.47 | −1.87; 0.93 | 0.493 | ||
Blood neutrophils, 109/L | −0.55 | −1.00; − 0.09 | 0.020 | ||
Blood eosinophils, 109/L | 2.81 | −0.48; 6.09 | 0.090 | ||
FEV1, % predicted | 0.04 | −0.01; 0.09 | 0.090 | ||
LCI at 2.5% | −0.30 | − 0.69; 0.08 | 0.117 | ||
ΔPD20 Clenil | Age, years | −0.06 | − 0.12; 0.00 | 0.050 | 0.48 |
Sex, male/ female | 0.80 | −0.42; 2.03 | 0.192 | ||
Current smoking, yes/no | −0.95 | −2.33; 0.43 | 0.170 | ||
Blood neutrophils, 109/L | −0.61 | −1.04; − 0.18 | 0.006 | ||
Blood eosinophils, 109/L | 3.04 | −0.06; 6.15 | 0.054 | ||
FEV1, % predicted | 0.03 | −0.01; 0.07 | 0.180 | ||
ΔPD20 Flixotide | Age, years | −0.03 | −0.08; 0.02 | 0.181 | 0.60 |
Sex, male/ female | 0.85 | −0.25; 1.96 | 0.125 | ||
Current smoking, yes/no | −0.33 | −1.51; 0.85 | 0.573 | ||
Blood neutrophils, 109/L | −0.78 | −1.13; −0.43 | 0.000 | ||
Blood eosinophils, 109/L | 3.53 | 0.88; 6.17 | 0.011 | ||
FEV1, % predicted | 0.002 | −0.04; 0.04 | 0.937 | ||
RV/TLC, % predicted | −0.03 | −0.06; 0.004 | 0.089 |