Skip to main content
Fig. 8 | RESPIRATORY RESEARCH

Fig. 8

From: LncRNA H19 promotes the proliferation of pulmonary artery smooth muscle cells through AT1R via sponging let-7b in monocrotaline-induced pulmonary arterial hypertension

Fig. 8

AT1R promotes the proliferation of PASMCs. PASMCs were transfected with 1000 ng of vector or pAT1R for 48 h (a, b). PASMCs were also transfected with 50 nM siCon or siAT1R for 48 h (c, d). Proliferation was analyzed by CCK-8 assay. AT1R, Ki67 and PCNA mRNA were detected by RT-qPCR. Values were presented as means ± SD from 3 independent experiments. *0.01 ≤ P ≤ 0.05 (different from the corresponding control); **0.001 ≤ P ≤ 0.009 (different from the corresponding control); ***P < 0.001 (different from the corresponding control)

Back to article page