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Table 2 Multivariate analysis of different prognostic factors in all stages and stage I ADC patients (two groups)

From: SOX30 specially prevents Wnt-signaling to suppress metastasis and improve prognosis of lung adenocarcinoma patients

ADC type

Variable

Comparison

Hazard ratio (95% CI)

P value

All stages ADC patients (n = 275)

Age

20–84 years

1.057 (1.025–1.090)

0.000

Gender

Male; Female

1.581 (0.789–3.169)

0.196

Histological grade

Grade 1–3

1.107 (0.712–1.722)

0.652

Tumor diameter

0.8–8 cm

0.973 (0.788–1.201)

0.796

Lymph node no

0–15

1. 014 (0.939–1.096)

0.720

Clinical stage

Stage I- IV

2.605 (1.852–3.663)

0.000

Tumor location

Left; Right

0.535 (0.298–0.960)

0.036

SOX30 expression

High; Low

0.874 (0.807–0.946)

0.001

Stage I ADC patients (n = 112)

Age

20–84 years

1.109 (1.011–1.216)

0.028

Gender

Male; Female

1.182 (0.155–9.002)

0.872

Histological grade

Grade 1; 2; 3

4. 702 (0.586–37.737)

0.145

Tumor diameter

0.8-7 cm

0.954 (0.402–2.268)

0.916

Tumor location

Left; Right

2. 605 (0.642–10.572)

0.180

SOX30 expression

High; Low

0.726 (0.567–0.929)

0.011

  1. Cox regression analysis was used to test independent prognostic contributions
  2. CI represents confidence interval. The p < 0.05 was considered statistically significant
  3. The entries in boldface indicate statistically significant