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Fig. 4 | RESPIRATORY RESEARCH

Fig. 4

From: SOX30 specially prevents Wnt-signaling to suppress metastasis and improve prognosis of lung adenocarcinoma patients

Fig. 4

SOX30 is negatively associated with CTNNB1 expression in ADC patients. a, b SOX30 expression is negatively associated with β-catenin expression in ADC patients but is not associated with β-catenin expression in SCC patients. The p value was measured with Pearson and Spearman correlations. c-f The expression of SOX30 and CTNNB1 was analyzed by RT-qPCR and WB in two ADC cell lines (A549 and SPC-A-1) and two SCC cell lines (H520 and H2170) with or without SOX30. ACTIN was used as an internal control. g The relationship of SOX30 and CTNNB1 expression was determined by IHC in ADC and SCC patient’s samples. Scale bars represent 20 μm

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