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Table 3 Microbiological variables

From: Clinical variables predicting the risk of a hospital stay for longer than 7 days in patients with severe acute exacerbations of chronic obstructive pulmonary disease: a prospective study

  Sputum sample collected in the previous year the hospitalisation Sputum sample collectedduring the hospitalisation
  Number of cases Normal LHSa (≤ 7 days) Prolonged LHSa (>  7 days) p value Number of cases Normal LHSa (≤ 7 days) Prolonged LHSa (>  7 days) p value
Patients with positive cultures 63 33 67 0.008 91 35 43 0.179
Number of pathogens: 0 373 51 49 0.031 346 51 49 0.138
 1 43 33 67   89 39 61  
 ≥ 2 20 35 65   2 50 50  
Pseudomonas aeruginosa 16 13 87 0.041 25 12 88 0.001
Pseudomonas aeruginosa colonisationc 9 0 100 0.002
Haemophilus influenzae 5 60 40 0.323 16 31 69 0.454
Streptococcus pneumoniae 7 43 57 0.677 18 61 39 0.037
Streptococcus spp. 5 20 80 0.657
Staphylococcus spp. 4 50 50 0.595 7 29 71 0.699
Pasteurella 2 50 50 > 0.999
Moraxella catarrhalis 3 67 33 0.256 3 100 0 0.059
Candida spp. 2 50 50 > 0.999
Aspergillus 2 50 50 > 0.999
Serratia 1 0 100 > 0.999
Escherichia coli 1 0 100 > 0.999
Mycobacterium no-TBC 1 100 0 0.396
Polymicrobial 20 35 65 0.848 8 50 50 0.708
Classification according to the conventional treatmentb: MSCT 31 45 55 0.026 51 51 49 0.014
 MRCT 20 15 85   30 23 77  
 MRCT colonisationc 10 10 90 0.009
Influenza B virus 2 50 50 > 0.999
Respiratory syncytial virus 7 43 57 > 0.999
Rhinovirus 7 29 71 0.450
Parainfluenza virus type 1 3 67 33 0.615
Parainfluenza virus type 3 3 0 100 0.499
Parainfluenza virus type 4 1 100 0 0.487
  1. aData reported as percentage related to number of cases for each of sputum sample. bPatients considered MSCT (for aminopenicillin with clavulanic acid, a macrolide or a tetracycline) or MRCT (Pseudomonas aeruginosa, MRSA, Stenotrophomonas maltophilia, Enterobacteriaceae producer of extended spectrum of beta lactamase and Acinetobacter baumannii) [2]. cColonisation was defined for a positive culture for the same microorganism in the sputum sample collected in the previous year and during hospitalisation. p value was calculated versus patients with a negative sample
  2. Abbreviations: LHS, length hospital stay; MRSA, methicillin-resistant Staphylococcus aureus; MSCT and MRCT, microorganisms sensible and resistant to conventional treatment