Variables | Normal LHS (≤ 7 days) (n = 213) | Prolonged LHS (> 7 days) (n = 224) | p value |
---|---|---|---|
Domiciliary medications | |||
Age, years | 73 [64.5; 78] | 72 [64; 78] | 0.857 |
Male, % | 82 | 80 | 0.637 |
BMI, kg/m2 | 27 [24.2; 29.4] | 27.6 [23.4; 31.5] | 0.486 |
Smoking habit: Current/Former, % | 41/59 | 39/61 | 0.598 |
Pack/year | 50 [40; 80] | 60 [40; 80] | 0.797 |
FEV1, % predicted | 44 [33; 63] | 42 [30; 58] | 0.126 |
FEV1/FVC | 49.5 [38.7; 62] | 49 [36; 62.7] | 0.823 |
GOLD 2017 stages: A/B/C/D, % | 32/32/15/21 | 18/39/12/31 | 0.015 |
LTOT, % | 22 | 32 | 0.013 |
mMRC dyspnoea grade | 2 [1; 3] | 2 [1; 4] | 0.001 |
COPD-SS severity questionnaire | 13 [8; 18] | 14 [9; 19] | 0.108 |
Charlson index | 2 [1; 3] | 2 [1; 3] | 0.750 |
Ischaemic heart disease, % | 11 | 9 | 0.501 |
Congestive heart disease, % | 9 | 18 | 0.008 |
Diabetes, % | 21 | 23 | 0.618 |
Chronic kidney failure, % | 4 | 7 | 0.257 |
Season of admission: Winter/Spring/Summer/Autumn, % | 40/14/29/17 | 45/16/25/14 | 0.508 |
Period of admission: years 2009–2011/2012–2104/2015–2017, % | 61/31/8 | 58/30/12 | 0.463 |
Previous AECOPDa | 0 [0; 1] | 0 [0; 2] | 0.286 |
Patients with ≥2 previous AECOPDa, % | 24 | 27 | 0.501 |
Previous AECOPD requiring hospitalisationa | 0 [0; 1] | 0 [0; 1] | 0.030 |
Patients with ≥1 previous AECOPD requiring hospitalisationa, % | 28 | 37 | 0.029 |
Onset of symptoms until admission, days | 4 [2; 7] | 5 [3; 7.75] | 0.035 |
Use of antibiotics previous admission | |||
In a period of one week before, % | 24 | 23 | 0.924 |
Days of treatment | 7 [3; 10] | 6 [3; 7] | 0.625 |
Penicillins/Fluoroquinolones/Macrolides/Cephalosporins/Others, % | 30/48/11/2/9 | 24/40/18/11/7 | 0.248 |
In a period of three months before, % | 40 | 53 | 0.044 |
Penicillins/Fluoroquinolones/Macrolides/Cephalosporins/Others, % | 23/63/5/0/9 | 34/45/10/8/3 | 0.149 |
Use of other drugs in a period of two weeks before admission | |||
Systemic corticosteroids, % | 12 | 13 | 0.867 |
Salbutamol, % | 4 | 14 | 0.001 |
Ipratropium bromide, % | 5 | 13 | 0.005 |
Domiciliary medications | |||
Salbutamol only, % | 3 | 3 | 0.922 |
Anticholinergic only, % | 5 | 5 | 0.819 |
LABA + Anticholinergic, % | 2 | 1 | > 0.999 |
LABA + ICS, % | 3 | 2 | > 0.999 |
Anticholinergic + ICS, % | 2 | 1 | > 0.999 |
LABA + Anticholinergic + ICS, % | 36 | 37 | 0.828 |