Skip to main content

Table 3 Association of admission sex and mineralocorticoid hormone metabolite levels with short- and long-term all-cause mortality in females with CAP

From: Dihydrotestosterone is a predictor for mortality in males with community-acquired pneumonia: results of a 6-year follow-up study

Females (N = 113)

All-cause mortality timepoint

30 days

3 years

6 years

HR (95%CI)

p value

HR (95%CI)

p value

HR (95%CI)

p value

Progesterone

 Cox regression analyses

0.34 (95%CI 0.004–25.46)

p = 0.621

0.24 (95%CI 0.08–0.71)

p = 0.010

0.44 (95%CI 0.17–1.14)

p = 0.093

17-OH-Progesterone

 Cox regression analyses

0.55 (95%CI 0.09–3.46)

p = 0.528

0.99 (95%CI 0.45–2.19)

p = 0.979

0.98 (95%CI 0.50–1.93)

p = 0.963

Aldosterone

 Cox regression analyses

0.29 (95%CI 0.04–2.14)

p = 0.226

0.64 (95%CI 0.30–1.39)

p = 0.263

0.81 (95%CI 0.43–1.53)

p = 0.516

DHEA

 Cox regression analyses

  

1.98 (95%CI 0.33–11.97)

p = 0.456

1.44 (95%CI 0.30–6.91)

p = 0.645

DHEA-S

 Cox regression analyses

  

0.69 (95%CI 0.22–2.19)

p = 0.529

0.55 (95%CI 0.23–1.31)

p = 0.178

Androstenedione

 Cox regression analyses

1.41 (95%CI 0.31–6.38)

p = 0.652

1.03 (95%CI 0.58–1.83)

p = 0.925

1.10 (95%CI 0.68–1.79)

p = 0.695

Testosterone

 Cox regression analyses

0.92 (95%CI 0.29–2.92)

p = 0.887

0.81 (95%CI 0.40–1.67)

p = 0.574

0.91 (95%CI 0.48–1.70)

p = 0.758

Dihydrotestosterone

 Cox regression analyses

  

1.78 (95%CI 0.60–5.25)

p = 0.296

1.20 (95%CI 0.56–2.59)

p = 0.638

  1. Data for multivariate Cox regression models are presented as HR (95% CI), p value; p values are considered statistically significant at p < 0.05. Bold values indicate statistical significance. All hormone metabolite levels were log-transformed and thus the HR corresponds to a 10-fold increase in these levels. CI confidence interval, DHEA dehydroepiandrosterone, DHEA-S dehydroepiandrosterone sulfate, HR hazard ratio
  2. The multivariate model is adjusted for age and comorbidities (coronary artery disease, cerebrovascular disease, chronic kidney disease, neoplastic disease)