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Table 1 Descriptive statistics for patients included in this analysis and for all treated patients in the WISDOM population

From: Spirometric changes during exacerbations of COPD: a post hoc analysis of the WISDOM trial

 

Analysis

All treated

Patients, n

360

2485

Males, n (%)

284 (78.9)

2049 (82.5)

Age, mean years (SD)

63.7 (8.5)

63.8 (8.5)

BMI, mean kg/m2 (SD)

25.4 (5.4)

25.2 (5.1)

COPD duration, mean years (SD)

8.7 (6.2)

7.9 (6.2)

Smoking status, n (%)

 Former smoker

236 (65.6)

1654 (66.6)

 Current smoker

124 (34.4)

831 (33.4)

Smoking history, mean pack-years (SD)

43.0 (21.6)

45.0 (24.3)

In-clinic post-bronchodilator FEV1, mean L (SD)

0.923 (0.285)

0.933 (0.297)

In-clinic post-bronchodilator FEV1, mean % predicted (SD)

32.7 (8.4)

32.8 (9.1)

Mean home-measured FEV1 in the period 6–8 weeks before index exacerbation, L (SD)

0.907 (0.321)

N/A

GOLD status, n (%)

 2

1 (0.3)

1 (0.6)

 3

218 (60.6)

101 (58.0)

 4

141 (39.2)

72 (41.4)

Number of patients included with a moderate exacerbation, n (%)

317 (88.1)

N/A

Number of patients included with a severe exacerbation, n (%)

43 (11.9)

N/A

  1. BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; GOLD, Global Initiative for Chronic Obstructive Lung Disease; ICS, inhaled corticosteroid; LABA, long-acting β2-agonist; LAMA, long-acting muscarinic antagonist; N/A, not applicable; SD, standard deviation