Fig. 1From: Spirometric changes during exacerbations of COPD: a post hoc analysis of the WISDOM triala Percentage change from period baseline in on-treatment daily FEV1 before and after first moderate/severe exacerbation. b Percentage change from period baseline in on-treatment daily FEV1 before and after first moderate exacerbation. c Percentage change from period baseline in on-treatment daily FEV1 before and after first severe exacerbation. All graphs show both treatments combined. Plots include patients whose first exacerbation after the ICS withdrawal visit was neither preceded by an exacerbation of any severity in 8 weeks prior nor followed by a further exacerbation of any severity within 8 weeks (56 days) after exacerbation. Day 0 is the day of the exacerbation. Period baseline is the mean of Days − 56 to − 36. FEV1, forced expiratory volume in 1 s; ICS, inhaled corticosteroids; SE, standard errorBack to article page