| |
C
|
COPD-TS
|
COPD-BS
|
|---|
|
Characteristics
|
|
Age (years)
|
67.26 ± 7.32
|
6.62 ± 7.79**
|
73.77 ± 7.46**/**
|
|
Height (cm)
|
147 ± 5.6
|
155.14 ± 7.92**/**
|
146.24 ± 5.28/**
|
|
Weight (kg)
|
58 ± 11
|
63.49 ± 13.52*
|
57.78 ± 11.68
|
|
BMI (kg/m2)
|
26 ± 6
|
26.52 ± 6.13
|
27.5 ± 5.28
|
|
Exposure and physiological characteristics
|
|
Tobacco index (pack-years)
|
0
|
37.28 ± 11.43
|
0
|
|
Biomass index (h-years of exposure)
|
0
|
0
|
361 ± 177
|
|
Exposure to biomass smoke (h-days)
|
0
|
0
|
7.17 ± 2.56
|
|
FEV1% pred
|
96.91 ± 13.36
|
52.40 ± 19.92***
|
58.40 ± 14.80*
|
|
FVC% pred
|
109.8 ± 9.1
|
79.49 ± 20.86*
|
83.10 ± 16.62*
|
|
FEV1/FVC ratio
|
92 ± 9.6
|
53.38 ± 12.62***
|
56.87 ± 12.11*
|
|
BODE
|
0
|
3.45 ± 2.86
|
2.91 ± 1.94
|
|
6MWT (m)
|
0
|
286.47 ± 174.23
|
318.91 ± 102.99
|
|
Clinical parameters
|
|
PaO2 (mm/Hg)
|
0
|
55.18 ± 14.65
|
55.1 ± 1.94
|
|
PaCO2 (mm/Hg)
|
0
|
40.88 ± 11.83
|
33.95 ± 5.62
|
|
SaO2 (%)
|
0
|
89.54 ± 4.19
|
89.16 ± 4.03
|
|
Glucose
|
95.0 ± 10.0
|
101.86 ± 24.5
|
109.94 ± 28.49**
|
|
C-reactive protein
|
0.28 ± 0.32
|
0.56 ± 0.62**
|
0.50 ± 0.51**
|
|
GOLD grades Case number (%)
|
|
I
|
0
|
5 (8.57)
|
7 (10)
|
|
II
|
0
|
27 (38.57)
|
41 (58.57)
|
|
III
|
0
|
23 (32.86)
|
16 (22.86)
|
|
IV
|
0
|
15 (21.43)
|
6 (8.57)
|
- Data are expressed as mean ± SD. Definition of abbreviations: BMI, body mass index; FEV1% pred, forced expiratory volume in the 1st sec (% predicted); FVC% pred, forced vital capacity (% predicted). Data were analyzed by one-way ANOVA and Tukey’s post hoc test. * P < 0.0001. ** P < 0.01. *** P < 0.05. * vs Control; /* COPD-BS vs COPD-TS
- Abbreviations: BMI body mass index, COPD-BS COPD by biomass smoke exposure, COPD-TS COPD secondary to tobacco smoking, FEV1% pred forced expiratory volume in the 1st sec (% predicted), FVC% pred forced vital capacity (% predicted)
