Cellular and acellular ex vivo lung perfusion preserve functional lung ultrastructure in a large animal model: a stereological study

Table 1 Oxygenation index and static compliance in vivo and during EVLP

Time point	Group	OI	C_stat [l/kPa]
In vivo	Control	520 ± 91	0.66 ± 0.17
	Ischaemia	487 ± 87	0.52 ± 0.14
	aEVLP	496 ± 64	0.65 ± 0.10
	cEVLP	469 ± 10	0.64 ± 0.19
2 h EVLP	aEVLP	482 ± 41	0.86 ± 0.12
2 h EVLP	cEVLP	506 ± 55	0.76 ± 0.27
12 h EVLP	aEVLP	496 ± 41	0.57 ± 0.08
12 h EVLP	cEVLP	514 ± 61	0.55 ± 0.12

Mean ± SD. In vivo data were obtained post thoracotomy immediately before lung explantation. Data of 2 and 12 h EVLP were obtained after 24 h cold ischemia and 2 and 12 h EVLP, respectively. Data of aEVLP and cEVLP groups were taken from [15]. OI did not differ significantly between groups (p = 0.912) or time points (p = 0.557). C_stat was not significantly different between groups (p = 0.549) but differed significantly between all 3 time points for EVLP groups (p = 0.004). OI oxygenation index at FiO₂ = 1, C_stat static lung compliance

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