Table 3 Risk factors associated with transplant-free 30-day and 90-day mortality in cirrhotic patients with pneumonia

Model 1: Baseline parameters

Model 1: Baseline parameters

Age

1.000 (0.982–1.018)

0.998

0.043

1.004 (0.981–1.027)

0.761

Multilobar infiltration

2.474 (1.125–5.443)

0.024

1.954 (0.760–5.027)

0.164

Bacteremia

2.88 (1.419–5.843)

0.003

0.001

2.293 (0.894–5.877)

0.084

0.002

Inappropriate empirical antibiotic use

8.894 (4.516–17.516)

<0.001

<0.001

7.645 (3.194–18.295)

<0.001

0.018

SIRS

3.061 (1.662–5.637)

<0.001

2.788 (1.278–6.084)

0.01

Ascites

2.931 (1.264–6.800)

0.012

1.918 (0.749–4.912)

0.175

Hepatorenal syndrome

3.847 (2.238–6.614)

<0.001

3.013 (1.494–6.076)

0.002

Hepatic encephalopathy

3.534 (2.073–6.023)

<0.001

3.416 (1.746–6.683)

<0.001

Model 2: Laboratory exam

Model 2: Laboratory exam

Age

1.000 (0.982–1.018)

0.998

0.013

1.004 (0.981–1.027)

0.761

0.082

WBC (10⁹ /L)

1.070 (1.048–1.091)

<0.001

<0.001

1.066 (1.040–1.092)

<0.001

<0.001

Platelet count (10⁹/L)

0.986 (0.979–0.994)

<0.001

0.989 (0.980–0.998)

0.012

INR

1.273 (1.190–1.362)

<0.001

1.242 (1.163–1.326)

<0.001

Total Bilirubin (mg/dL)

1.003 (1.001–1.004)

<0.001

0.002

1.003 (1.001–1.004)

0.004

Hemoglobin (g/L)

0.985 (0.975–0.996)

0.006

0.991 (0.978–1.004)

0.159

HCT

0.938 (0.903–0.976)

0.001

0.955 (0.912–1.000)

0.052

Creatinine (μmol/L)

1.003 (1.001–1.004)

<0.001

1.003 (1.001–1.004)

0.004

Glucose

1.075 (1.046–1.105)

<0.001

1.060 (1.019–1.102)

0.004

Model 3:

Severity scores

Model 3:

Severity scores

CLIF-SOFA score

1.319 (1.250–1.393)

<0.001

1.296 (1.213–1.386)

<0.001

Child-Pugh C grade

7.024 (3.193–15.450)

<0.001

5.198 (2.025–13.344)

0.001

MELD

1.096 (1.076–1.117)

<0.001

1.086 (1.061–1.112)

<0.001

MELD-Na

1.066 (1.050–1.083)

<0.001

1.062 (1.041–1.083)

<0.001

PSI scores

1.023 (1.018–1.028)

<0.001

1.024 (1.017–1.031)

<0.001

qSOFA≥2

6.248 (3.752–10.402)

<0.001

8.654 (4.546–16.474)

<0.001