|
Demographics data
|
|
Age(years), M ± SD
|
55.4 ± 13.7
|
57.9 ± 13.7
|
0.23
|
|
Sex m/f (% male)
|
52 (75.4%)
|
86 (64.2%)
|
0.12
|
|
Complications of cirrhosis
|
|
Ascites n (%)
|
60 (87.0%)
|
99 (73.9%)
|
0.03
|
|
Variceal bleeding n (%)
|
23 (33.3%)
|
29 (21.6%)
|
0.09
|
|
Spontaneous bacterial peritonitis n (%)
|
11 (15.9%)
|
18 (13.4%)
|
0.67
|
|
Hepatorenal syndrome n (%)
|
23 (33.3%)
|
4 (3.0%)
|
<0.001
|
|
HE n (%)
|
22 (31.9%)
|
9 (6.7%)
|
<0.001
|
|
Laboratory and radiographic findings
|
|
White blood cell count, 109 cells/L
|
13.8 (8.65–21.95)
|
8.1 (4.7–11.6)
|
<0.001
|
|
Platelet count, 109 platelets/L (IQR)
|
47 (22–75.5)
|
68.5 (40.8–101.5)
|
0.001
|
|
C-reactive protein level, mg/dL (IQR)
|
28.8 (14.7–72.0)
|
26.9 (11.6–65.5)
|
0.38
|
|
Creatinine, μmol/L (IQR)
|
154.0 (83.5–256.5)
|
66.5 (53.8–80.0)
|
<0.001
|
|
Albumin, g/dL (M ± SD)
|
24.8 ± 4.8
|
26.2 ± 4.9
|
0.06
|
|
Total Bilirubin, mg/dL (IQR)
|
252.0 (62.5–470.5)
|
38.0 (22.0–99.5)
|
<0.001
|
|
INR (IQR)
|
2.37 (1.62–3.38)
|
1.39 (1.22–1.73)
|
<0.001
|
|
Multi-lobar infiltration n (%)
|
55 (80.9%)
|
100 (75.8%)
|
0.48
|
|
SIRS n (%)
|
53 (76.8%)
|
68 (50.7%)
|
<0.001
|
|
ICU addmission n (%)
|
24 (35.3%)
|
8 (6.0%)
|
<0.001
|
|
EASL-CLIF definition ACLF
|
|
ACLF-1 (%)
|
13 (18.8%)
| | |
|
ACLF-2 (%)
|
28 (40.6%)
| | |
|
ACLF-3 (%)
|
28 (40.6%)
| | |
|
PSI score (IQR)
|
159 (117–195)
|
96 (86–115)
|
<0.001
|
|
Mortality
|
|
30-day mortality
|
32 (46.4%)
|
6 (4.5%)
|
<0.001
|
|
90-day mortality
|
48 (69.6%)
|
15 (11.2%)
|
<0.001
|
