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Table 2 Baseline characteristics and laboratory results of patients with ACLF and without ACLF

From: Pneumonia in patients with cirrhosis: risk factors associated with mortality and predictive value of prognostic models

Variables ACLF n = 69 (34.0%) NO ACLF n = 134 (66.0%) P value
Demographics data
 Age(years), M ± SD 55.4 ± 13.7 57.9 ± 13.7 0.23
 Sex m/f (% male) 52 (75.4%) 86 (64.2%) 0.12
Complications of cirrhosis
 Ascites n (%) 60 (87.0%) 99 (73.9%) 0.03
 Variceal bleeding n (%) 23 (33.3%) 29 (21.6%) 0.09
 Spontaneous bacterial peritonitis n (%) 11 (15.9%) 18 (13.4%) 0.67
 Hepatorenal syndrome n (%) 23 (33.3%) 4 (3.0%) <0.001
 HE n (%) 22 (31.9%) 9 (6.7%) <0.001
Laboratory and radiographic findings
 White blood cell count, 109 cells/L 13.8 (8.65–21.95) 8.1 (4.7–11.6) <0.001
 Platelet count, 109 platelets/L (IQR) 47 (22–75.5) 68.5 (40.8–101.5) 0.001
 C-reactive protein level, mg/dL (IQR) 28.8 (14.7–72.0) 26.9 (11.6–65.5) 0.38
 Creatinine, μmol/L (IQR) 154.0 (83.5–256.5) 66.5 (53.8–80.0) <0.001
 Albumin, g/dL (M ± SD) 24.8 ± 4.8 26.2 ± 4.9 0.06
 Total Bilirubin, mg/dL (IQR) 252.0 (62.5–470.5) 38.0 (22.0–99.5) <0.001
 INR (IQR) 2.37 (1.62–3.38) 1.39 (1.22–1.73) <0.001
 Multi-lobar infiltration n (%) 55 (80.9%) 100 (75.8%) 0.48
SIRS n (%) 53 (76.8%) 68 (50.7%) <0.001
ICU addmission n (%) 24 (35.3%) 8 (6.0%) <0.001
EASL-CLIF definition ACLF
 ACLF-1 (%) 13 (18.8%)   
 ACLF-2 (%) 28 (40.6%)   
 ACLF-3 (%) 28 (40.6%)   
PSI score (IQR) 159 (117–195) 96 (86–115) <0.001
Mortality
 30-day mortality 32 (46.4%) 6 (4.5%) <0.001
 90-day mortality 48 (69.6%) 15 (11.2%) <0.001