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Fig. 6 | Respiratory Research

Fig. 6

From: Role of SOD3 in silica-related lung fibrosis and pulmonary vascular remodeling

Fig. 6

Expression of vascular-specific genes. Analysis of vascular-specific gene expression in the lung of wild-type (Sod3+/+) and Sod3 deficient (Sod3−/−) mice. Expression of genes was analyzed 28 days following silica instillation. Whole lung mRNA levels for (a) endothelin 1 (ET-1), (b) insulin growth factor 1 (IGF-1), (c) platelet factor 4 (PF4), (d) platelet/endothelial cell adhesion molecule 1 (Pecam1) were determined using real-time PCR and normalized to beta-acting expression (Actin). The results are shown as mean ± SEM, *p < 0.05 when compared to control lung, One Way ANOVA with Holm-Sidak post test

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