Fig. 3

Effects of MitoTEMPO and VX765 on multiple ozone exposure-induced airway inflammation and and lung inflammation. a Effects of MitoTEMPO and VX765 on multiple ozone exposure-induced increased cell numbers in bronchoalveolar lavage (BAL) fluid, including total cells (TOTAL), macrophages (MAC), lymphocytes (LYM), neutrophils (NEU) and eosinophils (EOS). Each bar represents the mean ± SEM. b-d Effects of MitoTEMPO and VX765 on multiple ozone exposure-induced increased levels of cytokines in BAL fluid, including IL-1β (b), KC (c) and IL-6 (d). e Effects of MitoTEMPO and VX765 on multiple ozone exposure-induced inflammation scores in lung tissue. *P < 0.05, **P < 0.01, ***P < 0.001. One-way analysis of variance (ANOVA) with Bonferroni or Dunnett’s T3 post-test analysis was performed for comparisons between multiple groups