Fig. 2
Effects of MitoTEMPO and VX765 on multiple ozone exposure-induced lung function changes. The top panel indicates the experimental plan. Drugs were delivered 1 h prior to ozone exposure. Lung function analysis was composed of inspiratory capacity (IC) (a), functional residual capacity (FRC) (b), total lung capacity (TLC) (c), chord compliance (Cchord) (d), and percentage of forced expiratory volume (FEV) in first 25 and 50 ms of fast expiration (FEV25 and FEV50) of forced vital capacity (FVC) (e, f). *P < 0.05, **P < 0.01, ***P < 0.001. One-way analysis of variance (ANOVA) with a Bonferroni or Dunnett’s T3 post-test analysis was performed for comparisons between multiple groups