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Table 1 (abstract REGABS18026). Biometrics, Patient Reported Outcomes, Spirometry and Oscillometry

From: Abstracts from the 2018 Respiratory Effectiveness Group Summit

Biometrics

p/χ2

Healthy Group, n=36

Disease Group, n=11

 Age (mean years ± sem)

50

±

3

50

±

5

NS

 Sex (M : F)

9

:

27

2

:

9

NS

 BMI (kg/m2)

26

±

1

30

±

3

NS

 Smoking History

       

  Pack-Years

6

±

2

9

±

5

NS

  Current : Ex

12

:

24

4

:

7

NS

Patient Reported Outcomes

 COPD Assessment Test (CAT)

6.22

±

1.05

12.64

±

2.90

NS

 mMRC Dyspnea Scale (mMRC)

0.25

±

0.07

0.73

±

0.27

NS

 Asthma Control Test (ACT)

0.67

±

0.30

5.00

±

1.70

<0.005

 Chronic bronchitis (Yes : No)

2

:

34

2

:

9

NS

Spirometry

 FEV1 (L)

3.00

±

0.21

2.24

±

0.15

NS

 FEV1 (% predicted)

106

±

3

83

±

4

<0.005

 FVC (L)

3.74

±

0.24

3.19

±

0.18

NS

 FVC (% predicted)

112

±

3

100

±

6

NS

 FEV1/FVC (%)

80

±

1

71

±

4

<0.05

 MMEF (L/s)

2.92

±

0.25

1.76

±

0.26

NS

 MMEF (% predicted)

81

±

4

52

±

7

<0.05

Oscillometry

 R5 (median (IRQ) cmH2O/L/s)

3.64

(2.82, 4.25)

4.79

(4.05, 0.87)

<0.05

 R5-20 (cmH2O/L/s)

0.39

(0.14, 0.78)

1.10

(0.80, 1.70)

<0.05

 X5 (cmH2O/L/s)

-1.44

(-1.72, -1.14)

-2.04

(-3.28, -1.20)

<0.05

 Fres (Hz)

16

(13, 20)

25

(21, 28)

NS

 AX (cmH2O/L)

6

(5, 11)

16

(13, 28)

<0.001