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Table 2 Association between lung function and 10-Year CVD Risk (N = 4019)

From: Association of lung function with cardiovascular risk: a cohort study

Lung function parameters

Estimated changes (95% CI) by continuous lung function parametersa

Estimated changes (95% CI) by groups of lung function parameters

p trend

FEV1/FVC (%)

 

L4 (≥90)

L3 (80 ~ < 90)

L2 (70 ~ < 80)

L1 (<  70)

 

0.47 (0.34, 0.60)

0.00 (ref.)

0.78 (0.28, 1.28)

1.91 (1.24, 2.59)

3.82 (2.34, 5.30)

< 0.001

FVC (L)

 

Q4 (> 2.9)

Q3 (2.5~ 2.9)

Q2 (2.1~ 2.4)

Q1 (≤2.0)

 

0.24 (0.22, 0.26)

0.00 (ref.)

3.40 (2.71, 4.08)

4.83 (4.08, 5.58)

7.72 (6.92, 8.51)

< 0.001

FEV1 (L)

 

Q4 (> 2.5)

Q3 (2.2~ 2.5)

Q2 (1.9~ 2.1)

Q1 (≤1.8)

 

0.28 (0.25, 0.30)

0.00 (ref.)

3.33 (2.65, 4.01)

4.85 (4.10, 5.60)

7.96 (7.21, 8.71)

< 0.001

  1. Abbreviations: FEV1 forced expiratory volume in 1 s; FVC forced vital capacity, FEV1/FVC the ratio of FEV1 to FVC, CI confidence interval
  2. Adjusted for gender (male/female), height (continuous, m), weight (continuous, kg), abdominal obesity (yes/no), smoking amount (continuous, pack-year), drinking status (drinker/nondrinker), low density lipoprotein (continuous, mmol/L), physical activity (active/inactive), city (Wuhan/Zhuhai) and education levels (middle school or below, high school, university or above)
  3. aEstimated changes of 10-Year CVD Risk were calculated by each 5% decrease of FEV1/FVC or each 50-mL decrease of FVC or FEV1 in continuous analyses