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Fig. 5 | Respiratory Research

Fig. 5

From: Selective activation and proliferation of a quiescent stem cell population in the neuroepithelial body microenvironment

Fig. 5

Immunostaining for BrdU (red Cy3 fluorescence) and CGRP (green FITC fluorescence) in intrapulmonary airways 48 h after an intratracheal LPS (a, b) or sham instillation (c, d) in WT-Bl6 mice. a After LPS challenge, clustered BrdU-positive (divided) cells are observed in the epithelial layer (open arrowheads). b Additional CGRP immunostaining reveals that the intraepithelial BrdU-labeled cells are typically grouped around NEBs. c, d After a sham instillation, intraepithelial BrdU-positive cells also appear to be located in the neighborhood of NEBs (open arrowhead), but are less numerous than after LPS treatment. L: airway lumen, E: airway epithelium

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