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Table 1 Characteristics of the study population

From: Right heart size and function significantly correlate in patients with pulmonary arterial hypertension – a cross-sectional study

 

mean ± SD or n (%)

Demographics

Age

(years)

53

±

14.65

BMI

(kg/m 2 )

27.9

±

5.69

Gender

male

n (%)

21

 

(38.9)

female

n (%)

33

(61.1)

Diagnosis

IPAH

n (%)

31

(57.4)

HPAH

n (%)

8

(14.8)

APAH

n (%)

12

(22.2)

CTEPH

n (%)

3

(5.6)

WHO functional class

I

n (%)

1

(1.9)

II

n (%)

36

(66.7)

III

n (%)

17

(31.5)

PAH-targeted medication

Endothelin receptor antagonist

40

(74.1)

Phosphodiesterase-5-inhibitors

38

(70.4)

Soluble guanylate cyclase-stimulator

8

(13.0)

Prostanoids

6

(14.8)

Calcium channel blockers

2

(03.7)

Combination therapy

 

Mono

n (%)

18

 

(33.3)

Double

n (%)

31

(57.4)

Triple

n (%)

5

(9.3)

RHC

Rest

mPAP

(mmHg)

35.5

±

11.69

sPAP

(mmHg)

57.6

±

20.87

dPAP

(mmHg)

23

±

7.87

PCWP

(mmHg)

10

±

3.54

PVR

(dyn*sec*cm −5 )

393.4

±

235.03

CO

(l/min)

5.8

±

1.61

CI

(l/min/m 2 )

3

±

0.73

SVI

(ml/m 2 )

41.1

±

10.2

25 W

∆ CI

(l/min/m 2 )

1.2

±

0.67

50 W

∆ CI

(l/min/m 2 )

2

±

0.93

75 W

∆ CI

(l/min/m 2 )

2.6

±

1.15

Peak

mPAP

(mmHg)

56.5

±

15.91

sPAP

(mmHg)

90.2

±

28.36

dPAP

(mmHg)

36.1

±

11.56

CO

(l/min)

10.2

±

3.49

CI

(l/min/m 2 )

5.3

±

1.59

SVI

(ml/m 2 )

47.2

±

13.9

Echocardiography

RV area

(cm 2 )

20.1

±

5.59

RA area

(cm 2 )

16.8

±

6.62

TAPSE

(cm)

2.3

±

0.38

Cardiopulmonary exercise testing (CPET)

peak V’O2

(ml/min)

1126

±

428.88

peak V’O2/kg

(ml/min/kg)

14.1

±

3.92

sPAP Max

(mmHg)

81.8

±

27.87

 

6-MWD

(m)

423

±

113.09

Laboratory analysis

NT-proBNP

(pg/ml)

470.3

±

856.74

Pulmonary function test (PFT)

DLCOc SB

(% Soll)

58.6

±

17.25

DLCOc VA

(% Soll)

70.42

±

20.00

  1. IPAH = idiopathic pulmonary arterial hypertension, HPAH = heritable PAH, APAH = associated PAH, CTEPH = chronic thromboembolic PH, RHC = right heart catheter, BMI = Body Mass Index, RV = right ventricular, RA = right atrial, TAPSE = tricuspid annular plane systolic excursion, VO’2 = oxygen consumption, NT-proBNP = N-terminal pro brain natriuretic peptide, DLCOc SB = diffusing capacity transfer factor, DLCOc / VA = diffusing capacity transfer coefficient, mPAP = mean pulmonary arterial pressure, sPAP = systolic PAP, dPAP = diastolic PAP, PCWP = pulmonary capillary wedge pressure, PVR = pulmonary vascular resistance, CI = Cardiac Index, SVI = stroke volume index, HR = heart rate, SV = stroke volume, ∆ = difference