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Table 5 Calculated sensitivity and specificity for diagnosis of COPD defined by presence of radiographic CT evidence of smoking related lung disease, with emphysema > age adjusted upper limit of normal and/or functional small airways disease > ULN. N = 2972. LLN = lower limit of normal

From: Heterogeneous burden of lung disease in smokers with borderline airflow obstruction

Diagnostic criteria Sensitivity Specificity
FEV1/FVC < 0.7 0.85 0.72
FEV1/FVC < LLN 0.78 0.81