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Fig. 1 | Respiratory Research

Fig. 1

From: Upregulation of microRNA-17-5p contributes to hypoxia-induced proliferation in human pulmonary artery smooth muscle cells through modulation of p21 and PTEN

Fig. 1

Moderate hypoxia increases PASMC proliferation and upregulates miR-17-5p. a Cell viability was assayed by MTT assay after PASMCs were incubated under hypoxic conditions for 24 h and 48 h. b Cell proliferation was examined by BrdU assay. Moderate hypoxia (3% O2) stimulated PASMC proliferation. The results are the means ± SD of three independent experiments, and in each experiment, three parallel samples were analysed per group. c miR-17-5p levels were quantified by real-time PCR and normalized to RNU48 expression after hypoxia stimulation for 48 h. The results are the means ± SD, and the experiments were performed in triplicate and were repeated a minimum of three times. *P < 0.05, #P < 0.01

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Respiratory Research

ISSN: 1465-993X

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