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Fig. 7 | Respiratory Research

Fig. 7

From: Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation

Fig. 7

Comparison of the effect of VX-770/VX-809/FSK and TMX/ATP on CFBE cell current density. A: example of current/voltage relationships of cells in control conditions (squares), in the presence of VXs/FSK triangles) and in those treated with TMX/ATP (circles). B: The combination of TMX + ATP (n = 8) showed greater efficiency than VXs/FSK at increasing chloride membrane currents (n = 7; p < 0.001). Both treatments elicited highly significant increases in current density compared to the density in control conditions (n = 12)

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