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Fig. 1 | Respiratory Research

Fig. 1

From: Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation

Fig. 1

Total membrane current of 16HBE and CFBE epithelial cells elicited by ±80 mV voltage in 20 mV steps. Holding potential − 40 mV. a whole cell current recordings from single 16HBE cells in the control condition (top), after stimulation with 10 μM forskolin (middle) and after perfusion with the CFTR ion channel inhibitor Inh-172 (bottom). b whole cell current recordings from CFBE single cells in the control condition (top), after stimulation with 10 μM forskolin (bottom). c current/voltage relationships of 16HBE total membrane currents in the control condition (squares), after addition of 10 μM forskolin (circles; n = 6) and in the presence of Inh-172 (triangles; n = 3). d current/voltage relationships of CFBE total membrane currents in the control condition (squares n = 5) and after addition of 10 μM forskolin (circles; n = 7)

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Respiratory Research

ISSN: 1465-993X

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