Significant predictors of medically diagnosed chronic obstructive pulmonary disease in patients with preserved ratio impaired spirometry: a 3-year cohort study

Table 6 Significant factors for COPD diagnosis in PRISm

	Univariate analysis			Multivariate analysis
	OR	95% CI	P-value	OR	95% CI	P-value
Age (years)	1.14	(1.08, 1.21)	< 0.001	1.14	(1.05, 1.24)	0.002
Male
Height (cm)	0.93	(0.87, 0.99)	0.025	1.03	(0.92, 1.16)	0.564
Weight (kg)	0.94	(0.9, 0.99)	0.013	0.95	(0.89, 1.02)	0.153
Smoking history
Current smoking	0.61	(0.22, 1.66)	0.329
Pack-years	1.01	(0.99, 1.03)	0.490
Co-morbidity
Pulmonary tuberculosis	0.92	(0.12, 7.35)	0.940
Asthma	8.67	(2.41, 31.23)	0.001	5.87	(0.94, 36.56)	0.058
Lung function test
FVC % predicted	0.93	(0.89, 0.97)	0.001	1.01	(0.95, 1.09)	0.694
FEV₁% predicted	0.95	(0.9, 1.01)	0.071
FEV₁/FVC	0.001	(0.001, 35.7)	0.183
Self-reported respiratory symptoms
Cough for more than 3 months
Sputum for more than 3 months
Dyspnea	42.29	(3.61, 494.74)	0.003	8.88	(0.65, 121.7)	0.102
Wheezing	5.15	(1.75, 15.14)	0.003	4.56	(1.08, 19.35)	0.040
Chronic bronchitis

Statistically significant data are presented as bold
COPD chronic obstructive pulmonary disease, PRISm preserved ratio impaired spirometry, FEV₁ forced expiratory volume for 1 s, FVC forced vital capacity, OR odds ratio, CI confidence interval

ISSN: 1465-993X