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Table 4 Significant factors for COPD diagnosis in all subjects

From: Significant predictors of medically diagnosed chronic obstructive pulmonary disease in patients with preserved ratio impaired spirometry: a 3-year cohort study

 

Univariate analysis

Multivariate analysis

OR

95% CI

P-value

OR

95% CI

P-value

Age (years)

1.11

(1.09,1.13)

< 0.001

1.10

(1.07,1.13)

< 0.001

Male

1.02

(0.49,2.13)

0.954

   

Height (cm)

0.95

(0.92,0.97)

< 0.001

1.01

(0.97,1.05)

0.786

Weight (kg)

0.93

(0.91,0.95)

< 0.001

0.98

(0.95,1.01)

0.143

Smoking history

 Current smoking

0.92

(0.65,1.3)

0.631

   

 Pack-years

1.02

(1.01,1.03)

< 0.001

1.01

(1.00,1.02)

0.059

Co-morbidity

 Pulmonary tuberculosis

2.78

(1.79,4.31)

< 0.001

1.17

(0.66,2.10)

0.587

 Asthma

13.11

(8.27,20.79)

< 0.001

1.88

(0.97,3.64)

0.060

Lung function test

FVC % predicted

0.95

(0.94,0.97)

< 0.001

1.03

(1.01,1.05)

0.006

FEV1% predicted

0.93

(0.92,0.94)

< 0.001

0.95

(0.93,0.96)

< 0.001

 FEV1/FVC

0.001

(0.001,0.001)

< 0.001

   

Self-reported respiratory symptoms

 Cough for more than 3 months

37.80

(15.55,91.87)

< 0.001

2.40

(0.24,24.32)

0.458

 Sputum for more than 3 months

17.78

(7.81,40.52)

< 0.001

0.48

(0.02,10.90)

0.647

Dyspnea

25.49

(13.68,47.49)

< 0.001

3.07

(1.23,7.68)

0.017

Wheezing

7.83

(5.42,11.31)

< 0.001

2.90

(1.76,4.78)

< 0.001

 Chronic bronchitis

23.21

(10.67,50.5)

< 0.001

2.76

(0.07,109.05)

0.588

  1. Statistically significant data are presented as bold
  2. COPD chronic obstructive pulmonary disease, FEV1 forced expiratory volume for 1 s, FVC forced vital capacity, OR odds ratio, CI confidence interval