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Table 2 The clinical characteristics of participants

From: MiRNA expression profiles in healthy OSAHS and OSAHS with arterial hypertension: potential diagnostic and early warning markers

 

Training set

Validation set

Healthy controls

Healthy OSAHS

OSAHS with arterial hypertension

P value

Healthy controls

Healthy OSAHS

OSAHS with arterial hypertension

P value

Number

5

5

5

 

15

15

15

 

Age, (years)

39.4 ± 1.69

40.6 ± 3.17

43.8 ± 1.24

0.37

43.4 ± 2.1

43 ± 2.51

43.6 ± 2.33

0.98

Male, n (%)

5 (100%)

5 (100%)

5 (100%)

–

11 (73.33%)

13 (86.67%)

12 (80%)

0.68

BMI, (kg/m2)

23.5 ± 0.42

25.18 ± 1.18

25.99 ± 0.38

0.1

24.57 ± 0.46

25.56 ± 0.38

26.16 ± 0.56

0.07

Smoker, n (%)

2 (40%)

1 (20%)

1 (20%)

0.76

1 (6%)

2 (13%)

4 (27%)

0.32

Drinker, n (%)

0

2 (40%)

2 (40%)

0.3

2 (13%)

4 (27%)

7 (47%)

0.13

Cholesterol, (mmol/L)

4.42 ± 0.27

4.4 ± 0.14

3.86 ± 0.4

0.35

4.37 ± 0.19

4.42 ± 0.16

4.4 ± 0.24

0.99

Triglycerides, (mmol/L)

0.87 ± 0.05

1.44 ± 0.15

1.56 ± 0.25

0.04

1.23 ± 0.13

1.5 ± 0.13

1.48 ± 0.12

0.25

HDL, (mmol/L)

1.36 ± 0.14

0.95 ± 0.09

0.86 ± 0.09

0.02

1.26 ± 0.06

1 ± 0.03

1.01 ± 0.05

<  0.001

LDL, (mmol/L)

2.55 ± 0.15

2.88 ± 0.14

2.32 ± 0.35

0.28

2.45 ± 0.17

2.8 ± 0.13

2.85 ± 0.2

0.2

Glucose, (mmol/L)

4.4 ± 0.1

4.54 ± 0.15

4.72 ± 0.14

0.25

4.78 ± 0.12

4.93 ± 0.12

4.92 (4.7,5.2)

0.35

HbA1c, (%)

5.34 ± 0.17

5.56 ± 0.13

5.52 ± 0.08

0.47

5.33 ± 0.11

5.55 ± 0.06

5.46 ± 0.09

0.21

ESS

3 ± 1.48

13.8 ± 2.71

13.6 ± 2.09

<  0.001

7.27 ± 1.43

13.13 ± 1.65

8.6 ± 1.21

<  0.05

AHI, (events/hour)

1.96 ± 0.52

39.27 ± 6.14

45.27 ± 8.2

<  0.001

4.52 ± 0.56

47.44 ± 4.92

43.46 ± 5.25

< 0.001

Mean SaO2, %

97 (96,97)

92.8 ± 1.59

93.8 ± 0.66

< 0.05

96 (95.97)

92.47 ± 0.97

94 ± 0.5

<  0.001

Minimum SaO2, %

92.6 ± 1.08

69.4 ± 3.04

74.6 ± 4.61

< 0.001

90.4 ± 0.58

74 (60,82)

72.87 ± 2.02

<  0.001

  1. OSAHS Obstructive sleep apnea hypopnea syndrome, BMI Body mass index, AHI Apnea hypopnea index, SaO2 Oxygen saturation, ESS Epworth Sleepiness Scale, HDL High density lipoprotein, LDL Low density lipoprotein, HbA1c Glycosylated hemoglobin