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Table 2 Prevalence of exposure and outcome variables in the Isle of Wight cohort study and Kuwait University Allergy study stratified by sex

From: Leptin receptor gene polymorphisms and sex modify the association between acetaminophen use and asthma among young adults: results from two observational studies

 

IOW Study, % (n/total)

KUA Study, % (n/total)

Males

Females

P

Males

Females

P

Acetaminophen usea

 Never

55.2 (348/630)

35.5 (227/640)

<  0.001

20.7 (54/261)

13.1 (116/888)

<  0.001

 Medium

33.7 (212/630)

42.0 (269/640)

 

39.5 (103/261)

29.7 (264/888)

 

 High

11.1 (70/630)

22.5 (144/640)

 

39.8 (104/261)

57.2 (508/888)

 

Current Wheeze

 Yes

18.9 (122/646)

25.5 (168/658)

0.004

19.2 (49/255)

13.2 (112/846)

0.018

Current Asthma

 Yes

15.9 (103/646)

19.4 (128/659)

0.099

15.2 (39/257)

10.9 (96/878)

0.065

  1. IOW Isle of Wight study, KUA Kuwait University Allergy study
  2. aIn the IOW study, average times of acetaminophen use per month was reported and categorized as: never = none per month, medium = one or two times per month, and high = three or more times per month. In the KUA study, acetaminophen use in the past 12-months was reported as: never = none in the past 12-months, medium = at least once in the past12-months, and high = at least once per month in the past 12-months