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Table 1 Demographic clinical and imaging data from the whole systemic sclerosis patient population

From: A circulating cell population showing both M1 and M2 monocyte/macrophage surface markers characterizes systemic sclerosis patients with lung involvement

Demographic, clinical and imaging data in SSc PTs

Mean ± SD OR

number-percentage

Age (years, mean ± SD)

63 ± 13

Sex (females/males)

50/5

RP duration (years, mean ± SD)

5.8 ± 10

SSc duration (years, mean ± SD)

8.4 ± 6

SSc form = LcSSc/dcSSc (n = %)

36 = 65.5% / 19 = 34.5%

ANA (n = %)

55 = 100%

ACA (n = %)

20 = 36.4%

Anti-Scl-70 Ab (n = %)

23 = 41.8%

ILD at CT scan (n = %)

37 = 67.3%

Ground glass opacities, lower lobes (n = %)

13 = 23.6%

Ground glass opacities, upper lobes (n = %)

8 = 14.5%

Ground glass opacities, upper and lower lobes (n = %)

8 = 14.5%

Peripheral septal thickening (n = %)

31 = 56.4%

Apical fibrotic changes (n = %)

20 = 36.4%

Diffused fibrotic changes (n = %)

15 = 27.3%

Enlarged mediastinal nodes (n = %)

16 = 29.1%

Traction bronchiectasis and bronchiolectasis (n = %)

16 = 29.1%

FVC% (mean ± SD)

104 ± 24

DLCO/VA% (mean ± SD)

71.5 ± 20

sPAP mmHg (mean ± SD)

34 ± 7

Pro-BNP (pg/ml, mean ± SD)

1423 ± 5119

On immunosuppressive therapy (n = %)

32 = 56.1%

On glucocorticoids (n = %)

9 = 16.4%

On ERAs (n = %)

16 = 28.1%

  1. Data are expressed as means ±standard deviations or numbers = percentages of the total population. SSc Systemic sclerosis, PTs patients, RP Raynaud’s phenomenon, SD standard deviation, ILD interstitial lung disease, ANA Anti-nuclear antibody, ACA: Anti-centromere antibodies, Ab anti-Scl70 anti-topoisomerase antibody, CT computed tomography, FVC forced vital capacity, DLCO diffusing capacity of the lungs for carbon monoxide, sPAP systolic pulmonary artery pressure, pro-BNP prohormone of brain natriuretic peptide, ERAs Endothelin 1 receptor antagonists. No other vasomodulating therapies were used by the selected SSc patients