Skip to main content
Fig. 1 | Respiratory Research

Fig. 1

From: A circulating cell population showing both M1 and M2 monocyte/macrophage surface markers characterizes systemic sclerosis patients with lung involvement

Fig. 1

Ab anti Scl70 positivity: associations with FVC%, Pro-BNP blood values and mixed M1/M2 cells percentages. a and b, clinical associations of Anti-Scl70 Ab positivity with lower FVC% and higher pro-BNP values are shown. c and d show the representative dot plots from the flow cytometry analysis of the mixed M1/M2 CD204+CD163+CD206+TLR4+CD80+CD86+ cell subset is shown in patients with positive and negative Ab anti-Scl70. Significant differences (p = 0.027) are shown between average percentages of circulating mixed M1/M2 subset CD204+CD163+CD206+TLR4+CD80+ over total CD204+ cells, in Scl70+ vs Scl70- patients (e) and between percentage of circulating mixed M1/M2 subset CD204+CD163+CD206+TLR4+CD80+CD86+ over total CD204+ cells, in Scl70+ vs Scl70- patients (f). Anti-Scl70 = Anti-topoisomerase; FVC = forced vital capacity; pro-BNP = prohormone of brain natriuretic peptide

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us