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Table 1 Baseline characteristics, laboratory values and lung function parameters for patients and controls

From: Serum phosphate and phosphate-regulatory hormones in COPD patients

 

COPD patients (n = 40)

Controls (n = 79)

p-value

Male sex, n (%)

27 (67.5)

54 (68.4)

 

Age, years

63.5 ± 9.9

63.7 ± 9.8

0.908

Height, m

1.7 ± 0.1

1.7 ± 0.1

0.598

Weight, kg

83.2 ± 19.2

84.9 ± 16.5

0.624

Body mass index, kg/m2

27.3 ± 5.9

28.3 ± 5.1

0.387

GFR, mL/min/1.73m2

88.9 ± 11.3

82.7 ± 12.9

0.026

Creatinine, mg/dL

0.8 ± 0.2

0.9 ± 0.2

0.022

Urea, mg/dLa

30.1 ± 8.8

35.5 ± 14.2

0.013

Hemoglobin, g/dL

13.6 ± 1.5

13.0 ± 1.8

0.058

Lung functionb

FEV1, L

1.4 ± 0.8

2.6 ± 0,8

< 0.0001

FEV1, % predicted

47.5 ± 22.5

87.3 ± 17.6

< 0.0001

FEV1/FVC ratio, %

49.8 ± 14.2

80.6 ± 6.6

< 0.0001

TLC, L

7.7 ± 1.7

6.1 ± 1.5

< 0.0001

TLC, % predicted

118.7 ± 17.5

95.4 ± 18.1

< 0.0001

RV, L

4.9 ± 1.7

2.8 ± 0.9

< 0.0001

RV, % predicted

208.1 ± 62.5

123.0 ± 39.5

< 0.0001

VC, L

2.8 ± 1.0

3.3 ± 0.9

0.021

VC, % predicted

71.6 ± 21.4

84.3 ± 16.4

0.003

R total

0.76 ± 0.46

(0.65; 0.46–0.91)

0.31 ± 0.13

(0.3; 0.25–0.34)

< 0.0001

R total, % predicted

252.9 ± 155.2

(216.6; 153.2–302.9)

104.1 ± 43.1

(98.2; 84.4–114.9)

< 0.0001

  1. aUrea data available for 39 COPD patients; bOverall, lung function was assessed in 51 patients from the control group; data for TLC, RV, VC and R were available for 39 patients with COPD
  2. Values are number of patients (%) or mean ± SD, with median; Q1-Q3 values shown for skewed continuous parameters
  3. FEV1, forced expiratory volume in 1 s; Q quartile; R resistance; RV residual volume; VC vital capacity.