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Table 2 Baseline characteristics of the non-response and response patients

From: Elevated serum soluble programmed cell death ligand 1 concentration as a potential marker for poor prognosis in small cell lung cancer patients with chemotherapy

 

Non-response

Response

P value

Total (n)

112

138

–

Age (n)

64.2 ± 6.2

64.7 ± 5.5

0.472

Gender (n)

 Female

23

30

0.817

 Male

89

108

 

Smoking history (n)

 Non-smoker

42

65

0.127

 Smoker

70

73

 

Performance status

 0–1

93

125

0.076

 2

19

13

 

Tumor grade (n)

 High-middle

91

102

0.169

 Low

21

36

 

Tumor stage (n)

 LDa

68

75

0.312

 EDa

44

63

 

EGFR (n)a

 Negative

83

119

0.016

 Positive

29

19

 

KRAS (n)a

 Negative

101

133

0.046

 Positive

11

5

 

Serum PD-L1 (ng/ml)a

7.6 ± 2.5

6.6 ± 3.2

0.008

  1. aLD Limited disease, ED Extensive disease, EGFR Epidermal growth factor receptor, KRAS Kirsten rat sarcoma viral oncogene, PD-L1 Programmed death ligand 1