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Table 2 Effects of PR and at 1-year on exercise capacity, muscle force and health status

From: Short and long-term effects of pulmonary rehabilitation in interstitial lung diseases: a randomised controlled trial

 

Control

Rehabilitation

Rehabilitation

effect mean (95% CI ll,ul)

p- Value

6MWD (m)

 Baseline

491 (57)

462 (57)

 

0.36

 3 months

474 (57)

504 (57)

59 (33, 85)

< 0.001

 6 months

468 (57)

511 (57)

72 (36, 108)

< 0.001

 1 year

456 (57)

501 (57)

73 (28, 118)

0.002

Wmax (%pred)

 Baseline

71 (18)

61 (18)

 

0.15

 3 months

68 (18)

68 (18)

10 (2, 19)

0.01

 6 months

62 (18)

71 (18)

19 (8, 29)

< 0.001

 1 year

61 (18)

74 (18)

23 (10, 35)

< 0.001

SVC (%pred)

 Baseline

77 (21)

76 (21)

 

0.86

 3 months

77 (21)

78 (21)

2 (−2, 6)

0.23

 6 months

75 (21)

77 (21)

3 (−1, 7)

0.20

 1 year

76 (21)

79 (21)

4 (−0.2, 9)

0.06

DLCO (%pred)

 Baseline

42 (13)

45 (13)

 

0.31

 3 months

39 (13)

44 (13)

1.2 (− 2.4, 4.8)

0.52

 6 months

39 (13)

43(13)

0.9 (−3.6, 5.3)

0.70

 1 year

38 (13)

45 (13)

3.2 (−1.8, 8.2)

0.21

QF (%pred)

 Baseline

81 (27)

78 (27)

 

0.69

 3 months

81 (27)

88 (27)

10 (2, 18)

0.01

 6 months

83 (27)

90 (27)

10 (1, 18)

0.02

 1 year

88 (27)

94 (27)

9.5 (1, 18)

0.04

HF (%pred)

 Baseline

73 (17)

76(17)

 

0.56

 3 months

76 (17)

91 (17)

12.5 (5, 20)

0.002

 6 months

75 (17)

90 (17)

12 (4, 20)

0.004

 1 year

79 (17)

88 (17)

6 (−3, 15)

0.20

SGRQ total

 Baseline

40 (14)

42 (14)

 

0.68

 3 months

44 (14)

39 (14)

−7 (−13, −2)

0.005

 6 months

46 (14)

35 (14)

−12 (−19, −6)

< 0.001

 1 year

45 (14)

35 (14)

−11 (− 18, −4)

0.002

  1. Data are expressed as mean (SD) from the mixed model. The rehabilitation effect at each time point is the difference (and its 95% confidence interval) between changes from baseline in the rehabilitation group and in the control group. 6MWD six-minute walking distance, Wmax maximal workload, SVC slow vital capacity, DLco diffusion capacity for carbon monoxide, QF quadriceps force, HF handgrip force, SGRQ St George’s respiratory questionnaire. The rehabilitation effect at each time point is the interaction term between time points and group effects. The p-Value on the baseline line assesses differences in baseline values, the other ones assess the effect of rehabilitation at each time point. p-values in bold indicate a statistically significance