Fig. 2
From: Impairment of respiratory muscle strength in Berardinelli-Seip congenital lipodystrophy subjects
Maximum Inspiratory Pressure (MIP), Maximum Expiratory Pressure (MEP), and peripheral muscle strength (PMS) values of all BSCL subjects and after stratification according to the use of metreleptin from 2015 to 2017. a MIP, (b) MEP, and (c) PMS indices are expressed as % of predicted values. The results are represented as the mean ± SD. For the analysis of all BSCL subjects, the differences were considered statistically significant when *p < 0.05 using repeated measures ANOVA. For the analysis after stratification according to the use of metreleptin, the differences were considered statistically significant when *p < 0.05 using repeated measures ANOVA for the group without metreleptin and using unpaired Student’s t-test for the group with metreleptin