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Table 3 Multivariate analysis for predicting the risk of asthma exacerbation

From: Serum sST2 levels predict severe exacerbation of asthma

 

Univariate

 

Multivariatea

 

Hazard ratio (95% CI)

P-value

Hazard ratio (95% CI)

P-value*

High serum sST2 level (> 18 ng/ml)

9.2 (2.4–34.7)

0.001

5.5 (1.4–21.5)

0.015

Blood neutrophiliab (> 6000 μl)

26.6 (7.9–100.9)

< 0.001

18.9 (4.8–74.4)

< 0.001

  1. *P-values were calculated using Cox proportional hazard analysis
  2. aCorrelation coefficients: high serum sST2 level, 1.70; blood neutrophilia, 2.94, respectively
  3. bThe cut-off value for defining blood neutrophilia was optimized using the receiver operating characteristic curve analysis and calculating the Youden index
  4. CI confidence interval