Table 1 Baseline patient demographics for patients with lung function measurements and reference controlsa without ICS usage
From: Identifying the associated risks of pneumonia in COPD patients: ARCTIC an observational study
Variable | COPD with lung function data (N = 6623) | Reference, without ICS usage (N = 48,566) | p-value |
|---|---|---|---|
Age, mean years ± SD | 65.9 ± 10.1 | 64.5 ± 10.5 | < 0.0001 |
Female, n (%) | 3688 (55.7) | 26,792 (55.2) | 0.4699 |
Comorbidities below, n (%) | |||
Asthma, J45 | 974 (14.7) | 0 | < 0.0001 |
Cardiovascular disease, I00-I99 | 2514 (38.0) | 9932 (20.4) | < 0.0001 |
Hypertensive diseases, I10-I15 | 1707 (25.8) | 5941 (12.2) | < 0.0001 |
Ischemic heart diseases, I20-I25 | 584 (8.8) | 2052 (4.2) | < 0.0001 |
Cerebrovascular diseases, I60-I69 | 213 (3.2) | 1182 (2.4) | 0.0001 |
Diabetes Type I, E10 | 83 (1.2) | 757 (1.6) | 0.0568 |
Diabetes Type II, E11 + E13 | 418 (6.3) | 2049 (4.2) | < 0.0001 |
Hyperlipidemia, E78.5 | 161 (2.4) | 502 (1.0) | < 0.0001 |
Depression, F32 + F33 | 456 (6.9) | 873 (1.8) | < 0.0001 |
Osteoporosis, M80 + M81 | 139 (2.1) | 402 (0.8) | < 0.0001 |
Fractures, S2 | 356 (5.4) | 1968 (4.0) | < 0.0001 |
Charlson Comorbidity Index value, mean ± SD | 1.55 ± 0.8 | 1.26 ± 0.6 | < 0.0001 |
Health care utilization | |||
Number of outpatient hospital visits/year in 2 years before index date, mean ± SD | 1.53 ± 2.4 | 1.60 ± 3.7 | 0.1980 |
Number of contacts to primary care/year in 2 years before index date, mean ± SD | 12.0 ± 16.0 | 4.14 ± 13.6 | < 0.0001 |
ICS use, n (%) | |||
No ICS | 3385 (51.1) | NA | |
Low dose ICSb | 2189 (33.0) | NA | |
High dose ICSc | 1049 (15.8) | NA | |