Fig. 7

rIL-32γ modulates the interaction between integrins and the extracellular matrix. MRC-5 cells were plated on collagen-coated plates in the presence/absence of rIL-32γ. a Adherent MRC-5 cells were stained with crystal violet immediately after the adhesion assay (left) and optical density values from the dissolved crystals are shown (right). Similar results were obtained from three independent experiments. *P < 0.05 (b) Adherent cells were observed at 30 min under a microscope (original magnification: 100×). Similar results were obtained from two independent experiments. *P < 0.05, ***P < 0.0001 (c) Phosphorylation of FAK and paxillin was detected after MRC-5 cells attached to collagen-coated plates for 24 h in the presence/absence of rIL-32γ. Similar results were obtained from two independent experiments