Table 4 Significantly enriched gene sets
From: Transforming growth factor beta1 targets estrogen receptor signaling in bronchial epithelial cells
Name |  | TGF-β1 | TGF-β1 + E2 | E2 | |||
|---|---|---|---|---|---|---|---|
Pathway Type | Median Change | p-value | Median Change | p-value | Median Change | p-value | |
Airway Smooth Muscle Cell Contraction | Diseases | 1.14 | 4.72E-04 | 1.10 | 4.34E-03 | −1.01 | 3.96E-02 |
Alveolar Epithelial Cell Dysfunction | Diseases | 1.01 | 4.98E-02 | – | – | – | – |
Ca2+ Flux Regulation | Biological Function | 1.02 | 2.12E-07 | 1.06 | 1.40E-05 | −1.00 | 5.48E-09 |
Complement Alternative Pathway | Biological Function | −1.63 | 3.17E-04 | −1.49 | 2.64E-05 | −1.11 | 1.36E-03 |
Complement Classical Pathway | Biological Function | −1.34 | 2.27E-04 | −1.49 | 3.09E-05 | −1.15 | 4.87E-04 |
Extracellular Matrix Turnover | Biological Function | 1.55 | 2.26E-08 | 1.53 | 3.98E-07 | −1.04 | 6.86E-04 |
Histone Acetylation | Biological Function | – | – | – | – | 1.04 | 3.68E-02 |
Histone Phosphorylation | Biological Function | – | – | – | – | 1.05 | 2.99E-05 |
Neutrophil Chemotaxis | Biological Function | 1.09 | 1.27E-03 | 1.07 | 7.25E-03 | – | – |
NURF in Chromatin Remodeling | Biological Function | – | – | – | – | 1.06 | 2.48E-02 |
Skin Fibrosis | Diseases | 1.07 | 2.15E-02 | 1.06 | 1.64E-02 | – | – |
Vasodilation Activation | Biological Function | – | – | – | – | −1.00 | 3.34E-02 |