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Fig. 8 | Respiratory Research

Fig. 8

From: Transforming growth factor beta1 targets estrogen receptor signaling in bronchial epithelial cells

Fig. 8

TGF-β1 and E2 cause differential regulation of genes involved in extracellular matrix turnover. A gene set enrichment analysis using Pathway Studio of genes identified by RNA-Seq revealed that exposure to 5 ng/mL TGF-β1 (top) and 10 nM E2 (bottom) caused statistically significant (p < 0.05) enrichment of the extracellular matrix turnover pathway. Gray boxes denote cellular processes involved in the extracellular matrix turnover pathway. Red proteins indicate up-regulation and blue proteins indicate down-regulation as determined by RNA-Seq

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