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Table 5 Top 5 gene-sets significantly enriched in the NSIP group (GSEA)

From: Comprehensive gene expression profiling identifies distinct and overlapping transcriptional profiles in non-specific interstitial pneumonia and idiopathic pulmonary fibrosis

Gene Set

NES

p value

q value

Interferon-gamma-mediated signaling pathway (biological process)

2.48

< 0.001

< 0.001

Defense response to virus (biological process)

2.42

< 0.001

< 0.001

Response to type I Interferon (biological process)

2.30

< 0.001

< 0.001

Regulation of Interferon-gamma production (biological process)

2.27

< 0.001

< 0.001

Regulation of Interleukin-12 production (biological process)

2.26

< 0.001

0.005

  1. NES Normalized Enrichment Score
  2. q value: False Discovery Ratio
  3. The positive enrichment score indicated a correlation with the NSIP group. Ontologies are indicated in brackets