Table 3 Top 25 up-regulated genes in NSIP vs. IPF (SAM analysis)
NCBI Gene Symbol | NCBI Gene name | d | Fold change vs. NSIP group | q value |
|---|---|---|---|---|
LRP2 | LDL receptor related protein 2 | 4.49 | 2.12 | < 0.0001 |
IFI44L | interferon-induced protein 44-like | 3.99 | 2.67 | < 0.0001 |
SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 3.97 | 2.67 | 0.0237 |
SCN1A | sodium channel, voltage gated, type I alpha subunit | 3.96 | 1.97 | 0.0237 |
LNX2 | ligand of numb-protein X 2 | 3.86 | 1.52 | 0.0237 |
WARS | tryptophanyl-tRNA synthetase | 3.82 | 1.63 | 0.0237 |
SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 3.76 | 2.54 | 0.0237 |
FZD5 | frizzled class receptor 5 | 3.76 | 1.61 | 0.0237 |
PCDH9 | protocadherin 9 | 3.71 | 1.53 | 0.0237 |
F11 | coagulation factor XI//4q35 | 3.68 | 2.50 | 0.0237 |
RSAD2 | radical S-adenosyl methionine domain containing 2 | 3.63 | 2.26 | 0.0237 |
NECAB1 | N-terminal EF-hand calcium binding protein 1 | 3.60 | 2.48 | 0.0237 |
MFSD2A | major facilitator superfamily domain containing 2A | 3.57 | 1.97 | 0.0237 |
SDR16C5 | short chain dehydrogenase/reductase family 16C, member 5 | 3.50 | 2.23 | 0.0237 |
MOP-1 | MOP-1 | 3.48 | 1.60 | 0.0237 |
OAS-2 | 2–5-oligoadenylate synthetase 2 | 3.43 | 1.74 | 0.0237 |
PHACTR1 | phosphatase and actin regulator 1 | 3.43 | 1.55 | 0.0237 |
PIGA | phosphatidylinositol glycan anchor biosynthesis class A | 3.42 | 1.51 | 0.0237 |
IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 3.42 | 1.96 | 0.0237 |
C1orf162 | chromosome 1 open reading frame 162 | 3.40 | 1.54 | 0.0237 |
ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8 | 3.40 | 1.52 | 0.0237 |
FMO5 | flavin containing monooxygenase 5 | 2.44 | 2.44 | 0.0237 |
GBP4 | guanylate binding protein 4 | 3.34 | 1.92 | 0.0237 |
ZNF385B | zinc finger protein 385B | 3.32 | 2.36 | 0.0237 |
SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | 3.25 | 2.11 | 0.0237 |