Table 2 Prevalence of each symptom severity category in the whole population (‘Prev’) across all study visits, and the prevalence of undiagnosed COPD (‘COPD+’) within that symptom severity category. Sensitivity (‘TP’), specificity (‘TN’), positive predictive value (‘PPV’), and negative predictive value (‘NPV’) of each symptom when used alone to classify undiagnosed COPD (v. no COPD) using different severity thresholds
From: The diagnostic performance of patient symptoms in screening for COPD
Symptom severity | Cougha | Wheezeb | Phlegmc | Dyspnead | Total Symptomse |
|---|---|---|---|---|---|
Prev, COPD+ | Prev, COPD+ | Prev, COPD+ | Prev, COPD+ | Prev, COPD+ | |
0 | 72, 23% | 78, 21% | 83, 24% | 70, 23% | 45, 17% |
1 | 12, 29% | 10, 42% | 6, 30% | 26, 33% | 29, 28% |
2 | 3, 35% | 10, 49% | 1, 47% | 3, 56% | 16, 33% |
3 | 13, 42% | 2, 51% | 9, 39% | 1, 30% | 7, 50% |
4 | < 1, 67% | 4, 52% | |||
TP, TN PPV, NPV | TP, TN PPV, NPV | TP, TN PPV, NPV | TP, TN PPV, NPV | TP, TN PPV, NPV | |
0 vs. > 0 | 37, 76% 36, 77% | 39, 84% 46, 79% | 24, 85% 37, 76% | 40, 74% 35, 77% | 71, 50% 34, 83% |
≤1 vs. > 1 | 24, 88% 41, 76% | 23, 91% 49, 77% | 16, 91% 40, 75% | 7, 98%, 52, 75% | 41, 78% 40, 79% |
≤2 vs. > 2 | 21, 90% 42, 76% | 4, 99% 51, 74% | 14, 92% 39, 75% | 1, 99%, 38, 74% | 21, 93% 51, 77% |
≤3 vs. > 3 | < 1, > 99% 67, 74% | 7, 98% 52, 75% |