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Fig. 7 | Respiratory Research

Fig. 7

From: Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics

Fig. 7

c-Myc expression in pBECs from non-asthmatics and asthmatics cultured at ALI. Cells were infected with IAV H1N1 (MOI 5) and the expression of c-Myc was assessed at different time points. a and (b) represent mRNA expression of c-Myc at baseline and after IAV H1N1 infection (6–24 h) in non-asthmatics and asthmatics, respectively. The cycle threshold (Ct) value was normalized to 18S gene (∆Ct) and data are presented relative to corresponding non-asthmatics at baseline. *P ≤ 0.05 intra-cohort, and #P ≤ 0.05 inter-cohort at 24 h, using the Kruskal Wallis multiple comparisons test and Mann-Whitney test, respectively, N=5. c and (d) are immunoblots representative of baseline and 24 h after infection in non-asthmatics and asthmatics, respectively. e and (f) represent densitometric quantification of immunoblots. Data are presented relative to corresponding non-asthmatic levels at baseline, N = 4

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